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KMID : 0363619990200030087
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Journal of Korean Oriental Medicine
1999 Volume.20 No. 3 p.87 ~ p.93
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An Experiment of the Purgative Action of Rhei Rhizoma and Chungpesagan-tang
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Kim Jung-Jin
Park Eun-Kyung
Bae Hyung-Sup
Moon Sang-Kwan
Kim Young-Suk
Lee Kyung-Sup
Kim Dong-Hyun
Cho Ki-Ho
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Abstract
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Objectives: This study was conducted to analyze scientifically the purgative action of Chungpesagan-tang, which was widely used for stroke In Oriental Medicine.
Methods: The contents of sennoside A on the water-extraction of Rhei Rhizoma, the transforming activity of sennoside A to rheinanthrone by human intestinal bacteria, and the anti-costive activity of Chungpesagan-tang, Rhei Rhizoma and Yuldahanso-tang on mice were investigated.
Results: Rhei Rhizoma (Rheum palmatum, from China) had dose-dependent potent purgative action. Chungpesagan-tang containing this Rhei Rhizoma had more potent purgative action than Rhei Rhizoma only. However, Korean cultivated Rhei Rhizoma (Rheum undulatum) and Chungpesagan-tang containing this Korean cultivated Rhei Rhizoma had no purgative action.
Conclusions: These results suggest that Chungpesagan-tang polyprescription should be considered to enhance the purgative action of Rhei Rhizoma.
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KEYWORD
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Rhei Rhizoma, polygonaceae, purgative action, sennoside A, Chungpesagan-tang(Qingfeixiegan-tang), Yuldahanso-tang(Reduohanshao-tang)
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